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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56ba678a62e3e6f2a773759a8a20faa7267a7b064656dc5abf7d0b586d4b24a2' 
  AND token = 'Pphxyyn3Jr9buwGcuDXJXNuu1c8mBGfNYTDHmEY5myM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}