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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c4d95c0f88cd2c13f0c5fa2e9e5bde846ce80802d22c604ca3663f85a87f873' 
  AND token = 'N6IWrGOSBZCel7pDSlxjC1Ly719ZYG41QinzrkFCmiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}