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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d147b220260c657bdcde8c24f42dd1b21803e8aca38c9c02c7bf8c9eb79343' 
  AND token = '8L+hvtx7EU4pOdtma/YZczbnplVEWErIn3RVTvrOZ6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}