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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3edbdca2203928ca5a8958e76fd3c2863b1bc40c78c15a7a2e8e02322b44e9' 
  AND token = 'wsJjkG9o9jISUynSFE7EXKe3WS47LtijRJDwYsfBG5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}