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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1539ffbbdefd9b3f30b64b45720010f2d15c8552f60d8df471e3bcddad757bed' 
  AND token = 'MzSaZ1Y52Uwo/REnqvyOspX7JsNIW5XkPg52s3Eel0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}