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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4406f0f648085aa5fa56d2afabdf2e17902df5057b18556a255b0395adf77e9' 
  AND token = 'jG3he2Srn8aEVw8FENj2jurgjMC2zOb8dML8JF9IRIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}