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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3f9f37c5f31f4c49e1afbffbee7de5dec8e460bc78fee36c19d3c9726b43e0' 
  AND token = 'Z9knRCNW8HqXaCTWQuF1BY9huxTSxQf2bFZQrVZaji4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}