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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcce4cc612b1147e087d188cea9b08ca4ffd5017997e2ef60dc9bb63c0e9a615' 
  AND token = 'ceLMw2mGu/rW9rwEFfMTh8ns1AEcfQzsasHKGwgBdh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}