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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20e22b3488110187697569f7097332409fa179e740ff4aaafc008ffbc6a22096' 
  AND token = 'dDuRnRvjm6io9Zz8jtxNKOZe1vg7LDCuX5iIa/3O4Ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}