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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac0516e559d5dc8f22a2e218b81e94380d4fa429aa134e3d9eb099c544098c86' 
  AND token = 'fMBKhTSW6PFAzmGRZD2uSejwmyWIibGx7ldpbhl+HcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}