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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95f4c751e9995b5fa3dc69b4de0005491c96692700570452e9ea751f12b1f853' 
  AND token = '6PKiAvaYZ2CPMxNbhLvfREbTEO3RIOBKKagJLBmHOZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}