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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3660b0b2aef02dc5e665e534c71edc4e5873f0d0637380901df710fa3cdc3fa5' 
  AND token = '6+O65gAPC6adDIgVUQTVSjkkF9Arv6eUT5dqv1CAQ+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}