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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed099e796d20df0e893c781e74e8b5aa13981a05663f07fead4af944f3e1573' 
  AND token = 'Jj+la2q2pwkdNwsa19aztxJRW1CMlA8FCqcNvp/FjNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}