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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0709e97c8bbda292cc278ee377bd909d5c9680ed770b03bb8ff96fe8f9184eb' 
  AND token = 'UuSJ4KwLV8cjfsatAIQzjlSOGLnJFvqSszfMBe2Xw4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}