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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '737332e0220d6a14923754c37d71dbecc8641f58817ce68d0da2a7efa344b89e' 
  AND token = '3wvS0SMNrRxXBViy8b/HelNG9HTVlS/YIKgt6qc9dJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}