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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5815bb21c31664d90919fb32029450f27d3a47d796343080d616d098d8c36d99' 
  AND token = 'El6kF9X7dwN59Mv350nB50/rMuepiZWZqtTHDHttS7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}