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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ed8d820067607628b165e67312f719ecc7da5132c1a455a7cfcb90e5ec84df' 
  AND token = 'bHENYlRPsiXCL+xEK0d5I118iMnT5caEu8Wh59uFquo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}