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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f037a13e07ca83b25cc8202d0173a39901b9b3c18bbf3e4a2af1899db2c6cd1' 
  AND token = 'X2miCMgj+qTxD3VyayIjg+KlpCrpxA0ZglqiMjtkjZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}