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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbef49e3ba661bfa0d2783f624d2db2e1acdad30ab0792dfd7516a16c2e3beed' 
  AND token = 'HCV7ar9sGVSoz23jKRVCYHNskUprO8gUAgQC3TkvFGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}