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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19b41c6abaac2571b463c66a4dc21d488ce2dcc45f055ac21346743ddf0cf881' 
  AND token = 'GMS63Y7IeQhukVQUbT6FH/C3T8bAv4bHIYmWYe7l1hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}