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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7620460eebb5b00c3e4edebda8f935997a735fce9f4460de9fb5344c0b5f94db' 
  AND token = 'Tc20u7kuRaG8Wt+snbsBdVmcubMira2GR5RDIgimkaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}