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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1860caca12ebfa44b1d582e9321b0db0e59aaa9ee816ed9372821f51d5597f0' 
  AND token = 'uFem/Q5DRWQEEScj3nyUso/W8bAP3or0gIK81ktgd58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}