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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8485d3030e1f0e09bf52152319a3d5c6d875bfba03da858200c080a735774ca' 
  AND token = 'AVT38rnF/U7Hh6AHLrpGjN/XQQQj2TRW2xXASKSoOAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}