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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd017a4320de902057f10b98291ea0eda44222711f01fd921b4d120a16d26e20f' 
  AND token = 'Q7zH9n3oHkmf8doAJSmo/PM6a/fYZIthzLyCo2boIkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}