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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4708c590a6178bab6f45295e1dc4a21bafdf1618721b7e9c7636dd3465e0e1e4' 
  AND token = 'pb6TXF0BofkqRD92GhF8oWqHztXGZT+DDuu1axdszvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}