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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11fc862c8172d073efd25f37e4359d130578978dfb8361c9b1af564e70f7c703' 
  AND token = 'EQeiDz5VtijKCqHBGQrRPcnUSr4pAajVA0H8Yk1HEDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}