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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bb496135663f61c8985e86867ac0c40c221a2a9a863f0fa10bfaa7f6bf5f7a4' 
  AND token = 'ZPA+58nqwG7FBI/G44RC0E4MD14yWpnKF8Ys3n6MXr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}