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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e434c60d2d8b928abd67bc2d5fe79a2ba437a508a9bf8497ad06dc3f0a7da0fb' 
  AND token = 'gM9rMDa2aVUb2euGe0fzQ9GxCKi9uU16ebTtwF7lEmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}