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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '279fcd6125cc01bdca547a9249aaa34f7fa132f4eb231dda86aad8095961033d' 
  AND token = '9e0eRgH32NZAtDN28uNT0T9kt38vfSHv0S0y/vY9Tfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}