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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b2434e972490d9c06e7a2d77fd9644978d1e5bf4d8c902bc399e8d0f4435e63' 
  AND token = 'cejc3QYpYNrM+9W9qwR/4k5kcm1oLI5MZF1Wv4yXtSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}