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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d43b7148111bfb8a427283128c5fdb6faeb262b80cc896693f2b17f1ef12767' 
  AND token = 'kYoDZ7Y+p+6NE0RfjBBpOkhj/ZbIEhB6S39xNl9XE04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}