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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6907fb40f9690347bd93ad97f2e325937024093a0ec3f443b4c69b1c3bb49c65' 
  AND token = 'PHujF36MZW6C4qFFzPb2+owtlfTs+9p9MPtEDMLyEjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}