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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f35298fd9e0176dc2c485a5e6fe87bd8338e6ccccc826e2b360db3428901bc3' 
  AND token = 'EU6kqpqZXgzo0q7qw9ogee3bAAcxnlvTOmM67XzVFbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}