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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4365d98a2136a2dfd44dd40878c09becc12c4fe7a7783c9e6af647886a798c6c' 
  AND token = 'qqwCqRblw9xDZ/1QXB5TmwDyyIt3M3OMc9b7jvsCygw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}