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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fdcf4155fafda9144174e7767da14849c935df4751bf0761756c5822c2bb843' 
  AND token = 'uJL9kUYnVfKI5m1upms6/stzWVoiWuz4HJp3R7yya48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}