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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '193b8ac1731eec7bf6482536aa9b0eca30270dd3d6ff80da37a85939d211aed2' 
  AND token = 'flJtdMlf2txGvT5LirEMT0vndvHVB26NkECpNOynzy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}