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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ed2ed4182bdd2b5ad4e403a48531dab29724b991ce05994d4227273f9b8783' 
  AND token = 'YltZBmRnxh1XFtxPMhXTlKlHNq0O0yv69O0w6VM8BcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}