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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '626fb133380264fbb515801de790366070a8b38abe3c2891222d43f71ebd0df1' 
  AND token = '3dx2u2xRm0tk8Ekh2tD+MaLKEDIuyfM5iDEMF4iXXBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}