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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a249ace9ce932fbd9a1b57ec6daa5c9d6a895f8d03607618c942b17a9c616201' 
  AND token = 'v0LNEyb11gW8gIU/jz26MGg3pojutlKjNrzr3oN+qj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}