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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acdfbd38117bf17ca8e2f5f1b1a1571c521bf9f7e504685b00054e1427202406' 
  AND token = 'VhPRjXD5Usk6pg7b/dWGEuGcSm2t5I/f10MgZDgEGEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}