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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67ef03f849ebecfa2bc9c706019e139d4ee2298a1fc3af22aa8420180f417bb5' 
  AND token = 'othl4A3AFkwDfCH9L1va2n9RLSq10/KVCbIbwuDYfpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}