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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fb316e81df63b5781239c8e7e51a6f071dd0f29dbb3a240f69886af01da3be3' 
  AND token = 'ZpkvJuh/5IMskqyXWUJX+HQhjil/ida3gdbu9X059w8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}