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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c55425bc13668d72caa3bc2cbfd87f8ecd8b66da70de7b82fcefff254292538b' 
  AND token = 'L2PyAXU15asAGO6rSXBZMM3jHHxk9qz0NZrPfj1KDFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}