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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b778c8942713465c69714d447ebf666e493e4636bd58352c81e6f1b1c2935d8f' 
  AND token = 'mG1D5mrDEFV1UpxDDXnVeW+U54GuZNrzAdvEoUCsL9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}