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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14580e10a71406ec616cb50d3de5781d40598ba5938fe5f947013cd0cdf2c244' 
  AND token = 'cQw5LIwkzcieZOlnF1ipI/KsQRTdh9Ymg4Qtr55fSt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}