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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151c0f27673fa93acb6c1da8e9cab3caa117a8e7947e74f652e7653d488b6df5' 
  AND token = 'XrYL9Ge/c3PUksL8SwpW/lWfZcoUWMtxgmR6iq2Rj+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}