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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eaa20bf5c876d75200af7579a1a4c83a19e2b37ac3eeca67adb05bd3256c57b' 
  AND token = 'JIsL46cqNZNUM/2aMW9Ht6YpgBUwLpMQXBjLypyTVOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}