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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6329744bc1d18031680de1212053811056b7885792159c4bd08f386b1c0d8a5' 
  AND token = 'OknrzzJHsBqd0u2HtnJAQeTI2u3/4FxkCc2uXg7CAt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}