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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2748769a41d84e7d661e283ee1fdbf7f7b5a2375b8fce26accb812ee9082365d' 
  AND token = 'EmYP6OtwxetWEc/X/Do5EMSfxd2EcImBQ1fydcQgXnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}