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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5abd29856a937017eb039f2f9192c26c9b2aa157e6fe5108ce177c7060e8def0' 
  AND token = 'AJOY9D35G4H33rNwa40MqbM257hl8KbeNgzH5zGCFL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}